It may be counterintuitive that artificial sweeteners interfere with blood glucose regulation, but that they do was observed years ago in many studies. The precise mechanism remains unknown, but it looks as if the link is the effect on the gut microbiome. See, among others, https://www.diabetes.org.br/publico/images/pdf/artificial-sweeteners-induce-glucose-intolerance-by-altering-the-gut-microbiota.pdf